Run Time: 4 minutes Author: Dr. Jared Scott Educational Pearls: Semi-synthetic methadone used for chronic pain and nausea treatment. Partial agonist to opioid receptors, which decreases respiratory depression – theoretically decreases likelihood of respiratory arrest in a patient who overdoses. Patients on Buprenorphine chronically need Sufentanil for surgery – 10 times more potent than Fentanyl…